Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2
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منابع مشابه
P-11: Evaluation of Heat Shock Protein A2 in Male Rats before and after Varicocele Induction
Background: Varicocele is a major cause of male infertility, as it may impair spermatogenesis through several distinct pathophysiological mechanisms including hypoxia, renal-adrenal reflux, hormonal dysfunction, autoimmunity, oxidative stress and hyperthermia. HSP70s are members of the heat shock protein (HSP) family, which are considered intracellular chaperones. Their expressions can increase...
متن کاملThe role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition
One of the most common lesions present in the spermatozoa of human infertility patients is an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can now be readily by-passed by assisted reproductive strategies such as intracytoplasmic sperm injection (ICSI), recent large-scale epidemiological studies have encouraged the cautious use of this technology and hig...
متن کاملLEVELS OF ANTI-STREP TOKINASE AND ANTI-MYCOBACTERIAL HEAT SHOCK PROTEIN 65 KILODALTON (ANTI-MHSP 65) ANTIBODIES IN PATIENTS WITH AUTOIMMUNE DISEASES
Bacterial and viral triggers are suspected agents in the initial etiology of autoimmune diseases. There are some studies on the etiology of autoimmune disorders which have focused on streptococcal infection and a possible relation with microbial heat shock proteins (hsp) which show significant homology with human heat shock proteins. In addition, some serotypes of streptococci cross-react ...
متن کاملHeat shock protein 70 and anti–heat shock protein 70 antibodies in nasal secretions of patients with chronic rhinosinusitis
BACKGROUND The issue of heat shock protein (HSP) 70 and anti-HSP70 antibodies in chronic rhinosinusitis (CRS) has never been explored. OBJECTIVE To determine the nasal secretion (NS) levels of HSP70 and anti-HSP70 antibodies in patients with CRS with nasal polyps (CRSwNP) and patients with CRS without nasal polyps (CRSsNP), and to evaluate their associations with CRS clinical severity and cor...
متن کاملEvaluation of Salivary Level of Heat Shock Protein 70 in Patients with Breast Cancer
Introduction: Breast cancer is the most common cancer diagnosed among women worldwide. Increased molecular and genetic information about cancer has improved diagnostic, screening, and treatment methods for cancer. Heat shock protein 70 (HSP70) is overexpressed in breast cancer patients and involved in malignant properties of breast cancer. Due to the noninvasive nature of saliva collection and ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21124296